I gotta say that even though it doesn't currently integrate with any daw I use, I like the concept because it's different enough and seems a lot smoother in practise than some of the competition.
Even if you are making assignments manually, the big display makes changing setting much easier than a lot of other controllers I've used. When you go to the Control Edit mode, all of the settings are visible on the same page and there is a graphic representation of the control you are editing. This eliminates any guess work. We have also eliminated the need for any display pages that time-out if you know what I mean. So, if you are editing a control, it won't leave the Control Edit mode just because you haven't done anything for 3 seconds.
Doing stuff like editing zones and mapping pads is also graphical. So, not only does Panorama make it possible to map things flexibly but it gives you lots of feedback so that you always know where you are and what things are mapped too.
For those who are into using the drum pads, we have a Note Learn feature that allows you to change the notes that pads transmit. If you have a bunch of drum sounds layed out across the keyboard, you can use the keyboard to audition the sounds and then the pad will aquire the note assignment of the last key you hit. It's much more intuitive than selecting a note number via a menu.
There are lots of little touches like this that we implemented to make setup easier.