To the extent that 'time is money' in a given situation, If I needed to produce something
on the quick, with synth, samples, drums and guitar, the combo of Yoshimi synth,
DecentSampler, Hydrogen drums, and rakarrack for multi multi-effects would be my first choice. Free, but that's generally a linux only combo, and only an experienced or lucky shopper could compete finding windows-plugins with such sound quality and capabilities for under $100
So in windows, I'd choose Sonik Synth 2, DecentSampler, StiX for drums, and Guitar Rig for multi-effects, which is mostly the same workflow, 16-layer multi-timbral synths, simple load and play sampler, grid-and-pattern based drums, with guitar rig using a vertical rack vs rakarracks 8-effects per panel gui. One could use StiX-CM, and Guitar Rig Player to cut costs, and if lucky, find an old IK account with Sonik Synth included for sale.
I really prefer compact multi-timbral synth gui's over many multiple synth instances
of glorious gui's to achieve sounds in the same ballpark. But luckily there are hundreds of ballparks for the diversity of needs and preferences. and I admit it it just feels good to use glorious synth gui's, and their mostly great sounds
(when time is not quite money