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microsynth is a polyphonic multi-timbral microtonal SoundFont synthesizer, supporting seven types of tuning files, on-the-fly retuning, audio file recording, standard MIDI hardware controllers, and sequencing and notation software such as Sibelius and Finale, giving you total control of tuning in your music. It is also available in a mono-timbral version called microsynth-mini (tuning features are the same).
Check out the full documentation PDF at h-pi.com.