Alien can only successfully convert packages that conform to the now extinct Linux Standards Base (LSB). Since no distros (including even Debian) are complying with the LSB anymore, alien becomes less and less useful each year that passes.
I suspect that if I got to that point of desperation, I’d compile from source and then convert to RPM with FPM so that I can easily remove the package from my system if it doesn’t work.
So yeah, I don’t have a lot of confidence in alien.