I bought it because I wanted to have lower latency than USB interfaces provide. My use case is playing SW synths with a MIDI keyboard.
USB latency is ~5ms + at least 1.5ms for buffers (64 samples @44.1kHZ) and I thought that wasn't bad until I tried playing a real HW synth. It felt so much better and immediate! But I wasn't prepared to start collecting analog gear just yet and I kinda like my SW synths. That made me look into ways of lowering latency.
So I figured, if USB is the bottleneck then maybe PCIe sound cards would do better.
Apparently they do, but they come in 2 flavors: gaming focused cheap cards like Xonar/Audigy that lack common features like digital output and ridiculously expensive/overkill (for my needs) proffessional gear like RME and Lynx.
I did a bit of research and bought a Presonus Quantum 2626. It's a $600 thunderbolt audio interface and because I don't have a Mac I had to get an add-on Thunderbolt card for my PC which was another $100 on top. And a freaking $50 Thunderbolt cable (still sore about that).
Features up to 24-bit/192kHz operation, analog and digital (spidf + adat) i/o, phantom power, midi. All analog inputs and outputs are TRS/balanced. See manufacturer site for full specs if you're curious.
The promise was <1ms roundtrip latency and the Quantum 2626 delivers. Well, the software says it does, and it sounds like it does, but I'll probably measure that with an oscilloscope just out of curiosity.
Tried playing a guitar through it and it felt pretty much real-time.
In the end it is still overkill for my needs and it didn't cost much less than some RME/Lynx thing might have but it has features that I'll actually use, like midi i/o, phantom power for mics and the ability to plug an electric guitar directly into it. Also a nice big physical volume knob
Lowest buffer size is 16 samples and the simple VSTis I tried played without pops/clicks (i7-12700 cpu). Heavier ones required a 32-sample buffer for smooth playback, which is still quite good.
The interface comes with its own ASIO driver for Windows.
I've read reports that Quantum 2626 can't be used as a regular sound card for Youtube, Spotify, gaming etc, but it works just fine (on Windows 10 at least). Maybe previous driver/firmware revisions didn't support that but as of 2023/03 they do. Basically each pair of line outputs is presented as a separate sound card.
I can't speak about the quality of DAC/ADCs. They sound good but I'm not an audiophile or a sound engineer so my bar isn't all that high.
I have a few grievances with the Quantum 2626.
1) you can't do pass-through of inputs to outputs of the interface. It has to go through the software stack. I.E. it is useless without a computer.
2) there is only 1 thunderbolt port on the device so you can't daisy chain anything to it, I.E. it has to be the last device in the chain. Not a big deal for me since I don't have any other TB devices but still.
3) doesn't work on Linux and probably never will
Also, there was a gut-wrenching minute when I clicked "firmware update" and my PC bluescreened in the middle of the process. The update worked however (phew!).
Anyway. If you have a USB soundcard and playing your midi keyboard sounds just fine to you, don't ever try playing a HW synth
Note to PC users: the card requires a real Thunderbolt interface and won't work over usb-c. From what I can tell, Thunderbolt add-on cards are manufacturer-specific and require motherboard support (has to have a JTB header connector). I have a MSI B660M motherboard so I bought the MSI Thunderbolt 4x add-on card.
I will answer any questions if anyone is curious about some aspect I did not cover.
