A couple of comments on the comments:
JohnI don't know if you've played with the beta or not, but the combinator is an exremely impressive piece of kit. My guess is that you don't consider it a big deal. For me, it makes the upgrade. I could have left everything else out, but the combinator is awesome. If you haven't got to play with it, I hope you download the demo to see what you might be missing. I seriously doubt that you can do the things in Chainer that you can do with Combinator.
And to those of you that think it would be easy to port Reason to VST, IMHO I think that it would be an impossible task. Reason has zero to do with the VST standard...they would have to completely rewrite the plugins. I doubt that they would consider that a good use of their time. They obviously are doing just fine with their current business model, so it wouldn't make sense to change their "prime directive". I hope they stay with what they've got and improve its current architecture...more synths, disk streaming, advancements in the sequencer, etc.
I just live Like 4 so much that I don't mind using them in tandem

