Not being a fan of brown and being a huge fan of grey as a color that I can view for long periods without eye strain I would do something like this (taken from a screenshot, not an actual skin edit and not complete):

I'd probably also change the light buttons to a blueish hue and other tweaks. Not saying this is better than the default at all just saying that it would be better for my eyes.......no disrespect intended.......
The following link has a lot of skins for version 2.2 that required hacking the .dll. Now that changing skins is possible it would be great to be able to have official versions of these skins:
http://www.vstskins.com/skins/lennar-digital/sylenth1


