Regarding complexity, as you mention, it can indeed be very deep if you want to, but it is just an option. Some of our customers (who are scared to open Pandora's box) rarely get into the details and just work with presets from the main panel: in AXIOM you can just load effect chains presets and Amp sim presets (they work like amp models, even though they are not exact replicates of existing gear), and tweak the usual amp-style parameters, without getting into the details.
If you want to build your own amp model, you just open the amp editor (a built-in Destructor), and it is possible to create new models only by selecting existing presets for the preamp, destruction and "post filter"/cab sections. Of course, once become experienced with it, you usually want to get more control over the tone and start expanding modules one after the other...
There is also a new version coming soon, with a brand new way to create new tones without getting into the expert mode nor combining module presets, but we will probably talk about it later.
About factory presets: they indeed have to be adapted to your taste and playing. As you mentioned, there are several types of presets, not just global presets (which number has been limited on purpose: who uses multi effects factory presets out of the box?): several hundreds of predefined amp models and effects chains can be combined together to create your own tone, and that's the preferred way to get started (most of the settings I personally use are built this way, using stock amp and delay presets or sub-presets without any tweak). The upcoming presets browser will make this process more intuitive and much faster.
About Late Replies: I am very glad that you like it! It has probably the same pros and cons as Axiom regarding complexity, given its similar "Matryoshka doll" design: you can create your tone out of presets or sub presets for each section, or go deeper and deeper while opening up all the components to tweak the tone in details. "Gourmet Delay" sounds like a great name for a French company!
Oh and if you want to get really deep into plug-inception, you can load Axiom inside Late Replies inside Axiom inside...
Reference to Trash: it is funny that you mention it, because it was part of the long list of plug-ins that I tried a long time ago, looking for an "in the box" solution to replace all sort of physical preamps, multi-effects, tube amps and cabs. But it did not work for me. What's very different with Destructor is that each section is packed with presets based on typical guitar/bass/other gear responses, so creating your tone is less of a challenge, especially if you have no clue about how it is supposed to work. The other thing is that static wave shaping does not work if you want to get the typical dynamic response of amps most guitarists are used to (whether it comes from the preamp, the power amp, or just your ears that start collapsing because of the sound pressure): I can't play a crunch tone if it does not react to the attack.
About guitar tones & sound design: one thing that I found interesting is that if you look at the shapes of the curves for all the presets that you like (most of them have been synthesized from measurements of existing gear: what's a better starting point than what we guitar players have been used to?), you end up finding out how these shapes influence the tone. And once you really get used to it, you can dial in a tone in expert mode that sounds exactly as you would expect, very quickly. It does not take more time than learning how all these cabinets/microphones and amp models combinations are supposed to sound when you try to replicate the outer world "in the box".
About the "Destructor" name: it is indeed a bit misleading (it's historical)... But if you think about it, the heavy compression & EQing in clean amps or many of the non-linear processors that you can model with the plug-in (which do not necessarily sound like distortion) still completely destroy the original signal, but hopefully making it sound better



