I agree entirely with TheDude86. It's a totally different way of working that EQ or sample replacement. Those are familiar now, but certainly didn't start out that way. In my beta tests of Sasquatch it took some time to get my head around what it was doing, what it was great at, and what it was not-so-great at.
For me, Sasquatch has been a breath of fresh air. I use it just about every mix now. I'm fully addicted to Sasquatch and I wouldn't want to work without it regardless of whether I'm doing hip hop, metal, or dance.